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What is retinol? benefits, types, and how to use it.

01/09/2026 / Last Edited 07/09/2026

Author: Dr. Robert (Bob) Bianchini

What is retinol? Benefits, types, and how to use it.

Retinol is one of the buzziest skin care ingredients ever. But for all the attention retinol has gotten, many people still don’t know what it is, how it works, or even how to use it.

 

Understanding retinol is key to using it effectively and minimizing irritation, especially if you’re new to Vitamin A-based ingredients. Let’s explore the basics you need to know about the effects of retinoland how it can transform your nighttime skincare routinefor healthy skin.

 

 

What is retinol?

Pure retinol is a retinoid – a form of Vitamin A –itshands down the industrys gold standard ingredient for reversing the signs of skin aging. As an over-the-counter retinoid, retinol helps accelerate skin cell turnover, which can visibly improve uneven texture, fine lines, and discoloration over time. Retinol can benefit a multitude of skin conditions, but is most recommended for aging skins toreduce the appearance offinelines anddark spots for firmer, smoother and more even-toned skin. Treating acneis another benefit of retinol, it can help prevent dead skin cells from clogging pores.

 

 

Types of retinol and retinoids

Retinoids come in many forms; retinol, retinaldehyde, and retinoic acid, to name a few.

 

Regardless of which one you use,itsimportant to note thatenzymes in theskin convert all retinoids into retinoic acid.

 

This conversion process determines both the strength of the retinoid and how quickly results may appear. The more closely related a retinoid is to retinoic acid, the more quickly your skin will utilize it. AtDermalogica, we formulate our retinol creamsand serums with active ingredientsincluding either retinol esters or retinol to balance efficacy with skin tolerance and help irritation while maintaining skin health.

  • Retinoic Acid

    • This type of retinoid is the strongest and is available through a prescription. It can come in a topical form also known as “Tretinoin” which typically addresses signs of skin aging, or a pill form taken orally also known as the brand name Accutane or “Isotretinoin” which is typically prescribed for acne. These prescriptions have a high potential for skin irritation due to its direct activity in the skin without requiring conversion.
  • Retinol

    • Retinol is the strongest retinoid available without a prescription. While still highly effective, retinol is about 20% weaker than retinoic acid and is slowly converted into retinoic acid bytheskin. This slower conversion is why retinol is often better tolerated, especially when introduced gradually. This also means there is less skin irritation.
  • Retinyl Esters 

    • Retinyl esters like retinyl palmitate and retinyl propionate are the mildest retinoids. They take longer to convert to retinoic acid and carry a minimal risk of skin irritation. These forms are often recommended for beginners or sensitive skin types looking to ease into retinoid use. Learn more about our Retinoid Clearing Oil  - our comprehensive breakout treatment for an aging skin with retinoids and salicylic acid in one soothing oil for clearer, more vibrant skin overnight.  
  • Microencapsulated Retinol 

    • Retinol can be very sensitive to light (UV), air (oxygen), and heat causing the molecule to break down, losing potency and become ineffective. Dermalogica formulates with microencapsulated retinol and time-released encapsulated retinol to stabilize the retinol for maximum potency. Encapsulation also allows the retinol to be released gradually, reducing the likelihood of irritation while delivering consistent results. Microencapsulated retinol also creates an invisible shield on the skin’s surface to help reduce moisture loss, which is critical for reducing the appearance of wrinkles and fine lines. Try Age Reversal Eye Complex to target the eye area.

 

 

Why is retinol used?  

Skin aging occurs for several reasons – research suggests up to 50% of visible signs of skin aging come from our exposome. Your exposome includes factors such as climate, UV exposure, pollution, sleep, diet and stress. These factors can be healthy or unhealthy but a chronically unhealthy exposome can accelerate skin aging beyond what our DNA alone would dictate. 

 

In addition to this, as skin ages, cell turnover and collagen production slow down. Visible signs of skin aging (darkspots, fine lines, wrinkles, etc.) appear because our skin’s natural defense mechanismsweakendue to slower cell renewal and skin recovery. Retinol is widely used in skincare because it helps accelerate skin renewal, making it an effective option for addressing both intrinsic and environmentally driven aging.

 

 

How does retinol work on skin?  

Retinol encourages skin cell turnover and renewal. This gives skin a smoother, more even-toned appearance.Totolerate retinol,skin oftenhas tobuild up what are called retinoid receptors first.

 

These receptors are proteins that are naturally found in skin, and they help retinol do its work. With repeated, controlled use, skin becomes more efficient at responding to retinoids. Skin can build retinoid receptors through controlled exposure, which is whyitsoftenrecommendedto startslowlywith retinol products and build up to higher concentrations.   

 

 

How to use retinol  

    • Begin using retinol gradually. Start using retinol slowly to build up your skin’s tolerance to help reduce irritation. Apply retinol once per week, then every other night, gradually building up to nightly use to help your skin adjust.

    • Apply at night. Use retinol in your evening routine to align with your skin’s natural renewal cycle and reduce sun-related irritation.

    • Protect during the day. Always wear a broad-spectrum sunscreen (SPF 30 or higher) to protect newly renewed skin from UV damage.

    • Avoid other exfoliants.Unless recommended by a professional, do not layer retinol with additional exfoliating products to prevent over-irritation.

    • Support with hydration. Pair retinol with moisturizers or hydrating serums, such as hyaluronic acid, to maintain skin barrier health and reduce dryness.

    • Adjust for sensitive skin.

    Author Image forDr. Robert (Bob) Bianchini

    Dr. Robert (Bob) Bianchini

    Vice President of Technology and Development at Dermalogica

    Dr. Robert (Bob) Bianchini is Vice President of Technology and Development at Dermalogica, and has over 50 publications and patents in the skin care and dermatology fields. He is active in professional organizations, including the American Academy of Dermatology, American Chemical Society, and Society of Cosmetic Chemists. Dr. Bianchini earned his Ph.D. in Chemistry from Washington State University, completed postdoctoral research at Northwestern University, and pursued postgraduate studies at MIT’s Sloan School of Business.